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DR. CHIA-WEN (KEVIN) TSAO

Experience & Expertise

EDUCATION

Doctor of Philosophy (Ph.D.)                    May/2008

University of Maryland at College Park, College Park, MD, USA

Department of Mechanical Engineering


Master of Science (M.S.)                           Aug/2004

University of Colorado at Boulder, Boulder, CO, USA

Department of Mechanical Engineering


Bachelor of Science (B.S.)                        May/1998

Yuan-Ze University, Taoyuan, Taiwan

Department of Mechanical Engineering

EXPERIENCE

Professor                                                                                          08/2017 to now

Department of Mechanical Engineering, National Central University, Taoyuan, Taiwan

Director                                                                                             04/2019 to 01/2020   

Center for Academia and Industry Collaboration, National Central Universtiy,Taoyuan, Taiwan

Deputy Director                                                                              08/2018 to 04/2019   

Center for Academia and Industry Collaboration, National Central Universtiy,Taoyuan, Taiwan

Associate Professor                                                                       08/2013 to 07/2017

Department of Mechanical Engineering, National Central University, Taoyuan, Taiwan

Assistant Professor                                                                        08/2008 to 07/2013

Department of Mechanical Engineering, National Central University, Taoyuan, Taiwan

 Research Assistant                                                                       06/2005 to 05/2008

Maryland Microfluidic Lab University of Maryland, College Park, MD USA

 MEMS Engineer                                                                           08/2004 to 05/2005

Touch Micro System Inc. Taoyuan, Taiwan

 Research Assistant                                                                     08/2002 to 08/2004

Fluid Dynamics Laboratory, University of Colorado, Boulder, CO USA

 Mechanical Engineer                                                                 06/2000 to 06/2002

AeroVision Avionics, Inc.  Hsinchu, Taiwan

HONORS, AWARDS & RECOGNITIONS

2023 World's Top 2% Scientists - Single recent year impact    (全球前2%頂尖科學家)

2022 World's Top 2% Scientists - Single recent year impact    (全球前2%頂尖科學家)

2021 World's Top 2% Scientists - Single recent year impact    (全球前2%頂尖科學家)

Certificate in EMI (English as a Medium of Instruction) Skills, Cambridge English Language Assessment

‧ ”Polymer Microfluidics: Simple, Low-Cost Fabrication Process Bridging Academic Lab Research to Commercialized Production” is top 1% highly cited paper in the academic field of 「Engineering」 as of July/August 2020 (Web of Science)

‧2020 Best Paper Award, ICSS 2020 International Conference on Smart Sensors, Oct. 19-20, 2020

‧2019 Lab member S.M. Wang (M.S student) receive 2019 Humanoid Taiwan, Robo-one Champion

‧2018 Outstanding Alumni Award, Department of Mechanical Engineering, Yuan-Ze University

‧2017 National Central University Outstanding Research Award

‧2013 National Central University Outstanding Research Award

‧2008 National Central University Young Faculty Award  

‧“Bonding of thermoplastic polymer microfluidics” is the top cited paper Top 5 most cited articles from the time period 2008 and 2009 in Microfluidics and Nanofluidics (SCI, IF=3.504)

‧"Fabrication of nanostructured silicon by metal-assisted etching and its effects on matrix-free laser desorption/ionization mass spectrometry" Selected as Analytica Chimica Acta (SCI, IF=4.310) Featured article

Our research: 簡歷

GROUP MEMBER

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楊子頤

​機械工程學系碩士班二年級

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趙詠綺

機械工程學系碩士班二年級

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林千妤

​機械工程學系碩士班二年級

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鍾晨鴻

機械工程學系碩士在職專班

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陳冠呈

機械工程學系碩士在職專班

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江蕙瑀

機械工程學系碩士班一年級

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樊家維

機械工程學系碩士班一年級

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洪乃仁

機械工程學系碩士班一年級

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高上育

機械工程學系碩士班一年級

Our research: 團隊成員

PUBLICATION LIST

Journal Paper​

  1. Chia-Wen Tsao*, and Ping-Chin Shen “Maskless patterning of metal nanoparticles and silicon nanostructures by droplet deposition and etching process” Materials Advances, 2023, DOI: 10.1039/D3MA00380A

  2. Hu, Wei-Wen; Chen, Yen-Chi; Tsao, Chia-Wen; Chen, Shen-Liang; Tzeng, Chung-Yuh "Development of a multifunctional bioreactor to evaluate the promotion effects of cyclic stretching and electrical stimulation on muscle differentiation" Bioengineering & Translational Medicine

  3. Qun-Zhan Huang, Jyun-Cong Huang, Chia-Wen Tsao, and Shao-Yiu Hsu “Pore doublet micromodel experiments of evaporation influence on pre-event water entrapment and pre-event and event water interaction” Advances in Water Resources, 2023. 177: p. 104464.

  4. Wen-Pin Hu, Yi-Fang Lai, Cao-An Vu, Chia-Wen Tsao, Shin-Chen Pan, Chao-Min Cheng, Wen-Yih Chen “The paper/PMMA hybrid device with a microvalve-controlled design for exosome isolation and analysis” Talanta, 2023. 265: p. 124851

  5. Chia-Wen Tsao*, Chang-Yen Chang, Wei-Wen, Hu, and Yun-Shan Tian “Bonding of thermoplastic microfluidic device by water assistance” International Journal of Adhesion and Adhesives, 2023. 125: p. 103429

  6. Wei-Wen Hu, Shih-Yung Yang, Chia-Wen Tsao*, Shen-Liang Chen, Chung-Yuh Tzeng, “Deposition of polypyrrole on wrinkled polydimethylsiloxane to fabricate stretchable conductive membranes for multifunctional bioreactor applications” Progress in Organic Coatings, 2023. 181: p. 107573.

  7. Ahmed A. Shalaby, Chia-Wen Tsao, Akihiko Ishida, Masatoshi Maeki, and Manabu Tokeshi “Microfluidic Paper-Based Analytical Devices for Cancer Diagnosis” Sensors and Actuators B: Chemical, Volume 379, 15 March 2023, 133243

  8. Chia-Wen Tsao*, Chang-Yen Chang and Po-Yen Chien “Microwave-assisted solvent bonding for polymethyl methacrylate microfluidic device” Micromachines, 2022 Jul 17;13(7):1131.

  9. (Featured article) Kiran Giri and Chia-Wen Tsao*, “Recent Advances in Thermoplastic Microfluidic Bonding” Micromachines 2022, 13(3), 486

  10. Yi-Hsuan Shih, Shao-Yiu Hsu, Qun-Zhan Huan, Krzysztof Lamorski, Ming-Che Hu, Chia-Wen Tsao, Cezary Sławiński and Nima Shokri “Euler Characteristic during Drying of Porous Media” Drying Technology, 2022 40:4, pages 689-690.

  11. Chia-Wen Tsao*, You-Shan Zheng, Ya-Sen Sun, and Yu-Che Cheng “Surface-enhanced Raman scattering (SERS) spectroscopy on localized silver nanoparticles decorated porous silicon substrate” Analyst, 2021, 146, 7645-7652

  12. Chia-Wen Tsao* and Zhong-Ming Guo “Electrochemical Sensing on a Nanostructured Silicon Mass Spectrometry Surface” Austin Journal of Nanomedicine and Nanotechnology. 2021; 9(1): 1064

  13. Chia-Wen Tsao, Qun-Zhan Huang, Cheng-Ye Yu, Shao-Yiu Hsu, Krzysztof Lamorski, Liang-Cheng Chang, and Cezary Sławiński “The effect of channel aspect ratio on air entrapment during imbibition in soil-on-a-chip micromodels with 2D and 2.5D pore structures” Lab on a Chip, 2021, 21, 385

  14. Chia-Wen Tsao* and Zheng-Kun Wu “Polymer Microchannel and Micromold Surface Polishing for Rapid, Low-Quantity Polydimethylsiloxane and Thermoplastic Microfluidic Device Fabrication” Polymers 2020, 12, 2574

  15. Chia-Wen Tsao* and Wan-Ci Syu “Bonding of thermoplastic microfluidics by dry adhesive tapes” RSC Advances, 2020, 10, 30289 - 30296

  16. Wei-Wen Hu, Tun-Chi Chen, Chia-Wen Tsao, and Yu-Che Cheng “The effects of substrate-mediated electrical stimulation on the promotion of osteogenic differentiation and its optimization” The Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2018 1-13

  17. Chen, Pi-Yu; Hsieh, Chi-Ying; Shih, Chao-Jen; Lin, Yuan-Jing; Tsao, Chia-Wen; Yang, Yu-Liang "Exploration of Fungal Metabolic Interactions Using Imaging Mass Spectrometry on Nanostructured Silicon” Journal of Natural Products,2018, 81 1527–1533

  18. Chia-Yi Yen, Moh-Ching O. Chang, Zong-Fu Shih, Yi-Hsing Lien and Chia-Wen Tsao* “Cyclic Block Copolymer Microchannel Fabrication and Sealing for Microfluidics Applications” Inventions 2018, 3(3), 49

  19. Xu-Cheng Guo, Wei-Wen Hu­­­­, Say Hwa Tan and Chia-Wen Tsao* “A Stretchable Conductive Polypyrrole Polydimethylsiloxane Device Fabricated by Simple Soft Lithography and Oxygen Plasma Treatment” Biomedical Microdevices. 2018;20(2):30

  20. Chia-Wen Tsao*, I-Chao Lei, Pi-Yu Chen and Yu-Liang Yang “Piezo-Ring-on-Chip Microfluidic Device for Simple and Low-Cost Mass Spectrometry Interfacing” Analyst, 143, 981-988, 2018

  21. Shao-Yiu Hsu, Zhong-Yao Zhang and Chia-Wen Tsao* “Thermoplastic micromodel investigation of two-phase flows in a fractured porous medium” Micromachines 2017, 8, 38

  22. Heng-Dong Xi, Hao Zheng, Wei Guo, Alfonso M Gañán-Calvo, Ye Ai, Chia-Wen Tsao, Jun Zhou, Weihua Li, Yanyi Huang, Nam-Trung Nguyen and Say Hwa Tan “Active droplet sorting in microfluidics: a review”. Lab Chip, 2017,17, 751-771 (featured as cover image)

  23. Adrian J.T. Teo, Holden King-Ho Li, Nam-Trung Nguyen, Wei Guo, Nadine Heere, Heng-Dong Xi, Chia-Wen Tsao, Weihua Li, and Say Hwa Tan “Negative Pressure Induced Droplet Generation in a Microfluidic Flow-focusing Device” Analytical Chemistry , 2017, 89 (8), pp 4387–4391 (featured as cover image)

  24. Chia-Wen Tsao* “Polymer microfluidics: Simple, low-cost fabrication process bridging academic lab research to commercialized production” Micromachines 2016, 7(12), 225;

  25. Chia-Wen Tsao*, Xu-Cheng Guo and Wei-Wen Hu “Highly stretchable conductive polypyrrole film on three dimensional porous polydimethylsiloxane surface fabricated by simple soft lithography process” RSC Advances, 2016, 6, 113344-113351

  26. Chia-Wen Tsao*, Yuan-Jing Lin , Pi-Yu Chen and Yu-Liang Yang and Say Hwa Tan “Nanoscale silicon surface-assisted laser desorption/ionization mass spectrometry: Environment stability and activation by simple vacuum oven desiccation” Analyst, 2016,141, 4973-4981

  27. Chia-Wen Tsao* and Yueh-Pu Lee “Magnetic microparticle-polydimethylsiloxane composite for reversible microchannel bonding” Science and Technology of Advanced Materials, 2016, Vol. 17, No. 1, 2–11

  28. Chia-Wen Tsao*, Wen-Yih Chen, Chien-Han Lin and Yu-Che Cheng “Nanostructured Silicon Substrate for Desorption/Ionization on Silicon Mass Spectrometry Coupled with Titanium Oxide and Zinc Oxide Coated Magnetic Nanoparticles for Phosphopeptide Analysis” Journal of nanoscience and nanotechnolgy, Vol. 16, 1–7, 2016

  29. Chia-Wen Tsao* and Zhi-Jie Yang “High Sensitivity and High Detection Specificity of Gold-Nanoparticle-Grafted Nanostructured Silicon Mass Spectrometry for Glucose Analysis” ACS applied materials & interfaces, 2015 Oct 14;7(40):22630-7.

  30. Chia-Wen Tsao*, Yu-Che Cheng, and Jhih-Hao Cheng “­Fluid flow shear stress stimulation on a multiplex microfluidic device for rat bone marrow stromal cells differentiation enhancement” Micromachines 2015, 6(12), 1996-2009

  31. Shao-Li Han, Meng‑Jie Xie, Chih‑Cheng Chien, Yu‑Che Cheng, and Chia‑Wen Tsao* “Using MEMS‑based inertial sensor with ankle foot orthosis for telerehabilitation and its clinical evaluation in brain injuries and total knee replacement patients” Microsystem technologies,pp. 1-10, 2015/02/03 2015

  32. Chia-Wen Tsao*, Ke-Siang Chen, and Feng-Nan Hwang “Numerical Simulation of Droplet-Based Microfluidic Chip Interfacing with Laser Desorption/Ionization Mass Spectrometry Target Substrate” Micro & Nano Letters, IET, vol. 10, pp. 192-197, 2015

  33. Y.-C. Cheng, C.-W. Tsao*, M.-Z. Chiang, C.-A. Chung, C.-C. Chien, W.-W. Hu, R-C Ruaan and C. Li, “Microfluidic platform for human placenta-derived multipotent stem cells culture and applied for enhanced neuronal differentiation”, Microfluidics and Nanofluidics, (2014) 1-12

  34. Shao-Kuan Chen, Chih-Ang Chung, Yu-Che Cheng, Chi-Jung Huang, Wen-Yih Chen, Ruoh-Chyu Ruaan, Chuan Li, Chia-Wen Tsao, Wei-Wen Hu, and Chih-Cheng Chien “Toll-like Receptor 6 and Connective Tissue Growth Factor are significantly upregulated in mitomycin-C treated urothelial carcinoma cells under hydrostatic pressure stimulation” Genetic Testing and Molecular Biomarkers 18(6):410-6, 2014

  35. Atsushi Hattori, Tohru Yagi and Chia-Wen Tsao ­ “A Study on Encapsulation of Single-Cell into Fixed Droplets Using Triangular Microwells” IEEJ Transactions on Electronics, Information and Systems Vol. 134 (2014) No. 6 P 848-855

  36. Wei-Wen Hu, Yi-Ting Hsu, Yu-Che Cheng, Chuan Li, Ruoh-Chyu Ruaan, Chih-Cheng Chien, Chih-Ang Chung, and Chia-Wen Tsao “Electrical stimulation to promote osteogenesis using conductive polypyrrole films” Materials Science and Engineering C. 37 (2014) 28–36

  37. Shao-Kuan Chen, Chih-Ang Chung, Yu-Che Cheng, Chi-Jung Huang, Ruoh-Chyu Ruaan, Wen-Yih Chen, Chuan Li, Chia-Wen Tsao, Wei-Wen Hu and Chih-Cheng Chien “Hydrostatic pressure enhances mitomycin C induced apoptosis in urothelial carcinoma cells” Urologic Oncology: Seminars and Original Investigations, 32(2014)26.e17–26.e24

  38. Feng-Nan Hwang, Xiao-Chuan Cai, Yu-Lun Cheng, Chia-Wen Tsao* "A Parallel Fully Coupled Implicit Domain Decomposition Method for Numerical Simulation of Microfluidic Mixing in 3D", International Journal of Computer Mathematics, Volume 90, Issue 3, 2013

  39. Wei-Wen Hu, Wun-Jheng Syu, Wen-Yih Chen, Ruoh-Chyu Ruaan, Yu-Che Cheng, Chih-Cheng Chien, Chuan Li, Chih-Ang Chung and Chia-Wen Tsao “Use of Biotinylated Chitosan for Substrate-Mediated Gene Delivery” Bioconjugate Chem, 2012, 23 (8), pp 1587–1599

  40. Chia-Wen Tsao*, Cheng-Wei Chung and Zhi-Jie Yang “Preparation of nanostructured silicon surface for mass spectrometry analysis by an all-wet fabrication process using electroless metal deposition and metal assisted etching” International Journal of Mass Spectrometry, 321– 322 (2012) 8– 13

  41. Yi-Teng Hsiao, Jing-Hui Wang, Yi-Chun Hsu, Chien-Chun Chiu, Chien-Jung Lo, Chia-Wen Tsao, Wei Yen Woon “Collective hydrodynamics confinement in bacterial carpet microfluidic channel” Appl. Phys. Lett. 100, 203702 (2012)

  42. C. W. Tsao, C.H. Lin, Y.C. Cheng, C.C. Chien, and W.Y. Chen “Nanostructured silicon surface modifications for as a selective matrix-free laser desorption/ionization mass spectrometry” Analyst, 2012, 137, 2643-2650

  43. Chia-Wen Tsao* and Tzug-Yi Chen “Rapid polymer microchannel fabrication by hot roller embossing process” Microsystem Technologies, Volume 18, Issue 6, pp 713-722, 2012

  44. Yu-Che Cheng, Kun-Han Chen, Juo-Shin Wang, Wen-Liu Hsu, Chih-Cheng Chien, Wen-Yih Chen, and Chia-Wen Tsao* “Rapid Analysis of Abused Drugs Using Nanostructured Silicon Surface Assisted Laser Desorption/Ionization Mass Spectrometry” Analyst, 2012, 37, 654-661

  45. Chia-Wen Tsao* and Chia-Pin Chang “Effects of Metal Layer Morphology to Silicon Nanostructure Formation in Metal-Assisted Etching” Journal of Nanoscience and Nanotechnology, 2012,Volume 12, Number 3, March 2012 , pp. 2742-2749(8)

  46. W. Y. Chen, J. T. Huang, Y. C. Cheng, C. C. Chien, and C. W. Tsao*, "Fabrication of nanostructured silicon by metal-assisted etching and its effects on matrix-free laser desorption/ionization mass spectrometry" Analytica Chimica Acta, vol. 687, pp. 97-104, 2011.

  47. Huang, H.I., Cheng, Y.C., Chen W.Y., Tsao, C.W., Huang C.J., Liu, H.T., and Chien, C.C. “Comparative proteomic analysis of placenta-derived multipotent cells (PDMCs) and its differentiated neuron.” The Chinese J. Pain. 2010, 20(1), 01-11.

  48. Chia-Wen Tsao, Song Tao, Chien-Fu Chen, Jikun Liu, and Don L. DeVoe “Interfacing microfluidics to LDI-MS by automatic robotic spotting” Microfluidics and Nanofluidics, Volume 8, (2010) Issue 6, Page 777

  49. J. Liu, C.F. Chen, C.W. Tsao, C. C. Chang, C. C. Chu, and D. L. DeVoe ” Polymer Microchips Integrating Solid-Phase Extraction and High-Performance Liquid Chromatography Using Reversed-Phase Polymethacrylate Monoliths” Analytical Chemistry, 81 (7), pp. 2545-2554, 2009

  50. C.W. Tsao* and D. L. DeVoe “Bonding of thermoplastic polymer microfluidics” Microfluidics and Nanofluidics, 6,1–16 2009 (Top 5 most cited articles from the time period 2008 and 2009)

  51. C. F. Chen, J. Liu, L. P. Hromada, C.W. Tsao, C. C. Chang and D. L. DeVoe “High-pressure needle interface for thermoplastic microfluidics” Lab ON A CHIP, 9, 50 – 55, 2009

  52. C.W. Tsao, P. Kumar, J. Liu and D.L. DeVoe "Dynamic electrowetting on nanofilament silicon for matrix-free laser desorption/ionization mass spectrometry" Analytical Chemistry, vol. 80, pp. 2973-2981, 2008

  53. C.W. Tsao, J. Liu and D.L. DeVoe " Droplet formation from hydrodynamically coupled capillaries for parallel microfluidic contact spotting " Journal of Micromechanics and Microengineering, vol. 18, pp. 025013, 2008   

  54. C.W. Tsao, L. Hromada, J. Liu, P.Kumar and D.L. DeVoe "UV/Ozone Surface Treatment of PMMA and COC Microfluidic Substrates" LAB ON A CHIP 7 (4): 499-505 2007

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CONTACT US

If you want to contact us...

We are located in the Department of Mechanical Engineering, National Central University, Taiwan


Prof. Chia-Wen (Kevin) Tsao

Email: cwtsao@ncu.edu.tw

Tel: +886-3-4267343


Office Address: Room E4-366 No. 300, Zhongda Rd., Zhongli District, Taoyuan City 32001, Taiwan

uf2 Lab Address: Room E4-252 No. 300, Zhongda Rd., Zhongli District, Taoyuan City 32001, Taiwan
uf2 Lab TEL: +886-3-4227151 ext.37317

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